Male reproductive organ come in all shapes and, sizes and, so are the Erections and ejaculations. Most men experience erection problems at some stage of life. Most of the time, the occasional loss of erection is normal. However, work stress and anxiety, relationship problems, sexual boredom or alcohol and drug can result in your penile organ not responding to arousal.

Men also do masturbation as a way of relaxing and relieving, but if you start having problems getting or maintaining an erection even while masturbation, it may be an alarming signal. Fortunately, there's a lot of help available that promises relief to men and their partners, encouraging them to solve erectile dysfunction. Cenforce 100mg is a trusted name of medication to treat erectile dysfunction.


Description and Mechanism of Action of Sildenafil

The mechanism of action is triggered by the onset of sexual stimulation. Patients with erectile impotence generally have anatomical concerns related to the blood supply system in the penile tissue. At times, erection is too soft for penetration, or too short in duration, or the erectile response is not present.

In patients with ED, the PDE5 destroys the cGMP prematurely. The cyclic GMP is responsible for the vasodilation and the smooth muscle relaxation in the penile region, so it premature disintegration affects the erectile response adversely. Sildenafil citrate is the active ingredient in Cenforce, used to treat erectile dysfunction (ED). It acts as an inhibitor of phosphodiesterase-5 (PDE-5). PDE-5 is responsible for the degradation of cGMP. During sexual interaction nitric oxide is released which is responsible for the production of cGMP. The main work of cGMP is to increase the blood flow in the penile region. In ED condition, the production of nitric oxide is stopped or reduced, leading to dysfunction in erection.

 

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Cenforce (Sildenafil citrate) works on the PDE 5 and get reduced its amount to allow the production of cGMP for better erection.

Recommended Doses and Duration of Therapy

Cenforce devoured in two doses 100 mg & 200mg. The main stream response from the patients is noted for the 100 mg, likewise you can increase or decrease the dosage. In some of the patients, however, greater doses of Sildenafil Citrate are required. That’s where the 200 mg of Sildenafil doses comes into play. Patients with more severe erectile failures tend to require greater doses.


Manufacturers recommend that Sildenafil products be taken without meals. However, patients can administer Sildenafil with or without food. Alcohol, still, should not be co-administered with Sildenafil, due to possible antagonistic effects.

Cenforce Side effects and Warnings

Due to Sildenafil’s PDE5 inhibition capability, there are also some body parts affected by this action. Nominal side effects such as facial flushing, headaches, dizziness, blurred vision, dyspepsia, are seen at times. Severe adverse side effects of Sildenafil Citrate are rare.
Precautions

Nitrate medications are known as notorious, for their adverse interaction with Sildenafil. If you are a patient of blood pressure problems, angina or taking cardiovascular medicines containing nitrates then you must avoid to administer Sildenafil. You should avoid intake of grapefruit juice while use of this medication.

Buy Cenforce 100, 200 mg Online to bring more closeness and pleasure in your romance between the bed sheets.