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Mifeprex - Mifepristone

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Starting from $123.33

Quick Overview

Mifeprex contains Mifepristone; it acts by blocking the receptor named as Progesterone (which is important during the pregnancy).

Quantity Strength Price Unit Price
1 Kit Mifeprex - Mifepristone $130.00 $130.00
2 Kit Mifeprex - Mifepristone $250.00 $125.00
3 Kit Mifeprex - Mifepristone $370.00 $123.33

Mifeprex is an oral medication used to induce the labor to abort the child of less than 9 weeks. Mifeprex Contains Mifepristone as an active ingredient and it is an anti progesterone drug. Progesterone is chiefly important for the pregnancy. Progesterone also termed as pregnancy hormone as it nurture the fetus. This drug just inhibits the mechanism of progesterone.

Mechanism of actionof Mifeprex :

Mifeprex contains Mifepristone; it acts by blocking the receptor named as Progesterone (which is important during the pregnancy). So, the biological response of the progesterone become inactive and then softens and dilates the cervix. Due to this, decidual necrosis takes place, i.e. causes the detachment of placenta, which finally induces the labor and causes abortion. Mifepristone also have property like weak anti glucocorticoid and anti androgenic activity.

Contraindications:

  • Don't have allergy to the active or inactive ingredient of Mifeprex.
  • Suffering from abnormal bleeding
  • Administered any anticoagulant drugs like Heparin.
  • Suffered from severe adrenal failure.
  • Taking long term steroid therapy
  • In case of an ectopic (tubal) pregnancy.
  • Hemorrhagic disorders.
  • Inborn porphyries

 

Mifeprex interactions:

But sometimes it may interact with Mifeprex and alters the action of each other.  These drugs are:

  • Anti fungal Drugs: Ketoconazole, Itraconazole
  • Antibiotics: Erythromycin
  • Alcohol or grapefruit juice

Storage:

  • Should be stored in air tight container and at room temperature varied from 15 to 30° C.
  • Should be protected from heat and humidity.

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Mifeprex is a solid dosage form, available in the form of tablet. Mifeprex can be administered by oral route. Mifeprex administered three doses on first day. If the pregnancy terminated successfully, then there is no need of further medication. But in case, Pregnancy can't be terminated then the medication with Misoprostal carried out.  

Overdose:

The safe dose of the Mifeprex is mentioned in the above division. Patient should avoid taking more than one dose at a time. It may create habitual or addiction problem in the patients.

Sign and symptoms of the overdose:

  • Fluctuations in breathing and heart rate
  • Fainting
  • Chronic drowsiness and dizziness
  • Feeling of nausea and sleepiness
  • Occurrence of seizures
  • Bradycardia
  • Weakness with or without abdominal pain

Missed dose:

In case of missed any dose, then take it  as soon as possible. But, if becomes too late, then skip the dose and administered next drug on time. Don't take double dose of the medicine at a time.

Those unwanted effects developed from the medication of Mifepristone, along with the remedial effects. These effects are not beneficial for the health of the patient. These unwanted effects are:

  • Acute side effects: Temporary blood clots formation, severe cramping, feeling of vomiting and nausea, severe Headache or migraine, diarrhea, feeling faint or dizzy, tiredness, chills, and hot flashes, sweating or shivering.
  • Chronic side effects: Heavy vaginal bleeding, uterine hemorrhage, infection and sepsis.

Some precaution should be taken to avoid side effects developed from the Mifeprex. Such precautions are:

  • Avoid alcohol or any other fermented drink after taking this drug
  • Avoid driving after taking Mifeprex.
  • Suffering from liver or kidney disorder.
  • Don't crush or break the dosage form for administering.
  • Don't administer if patient suffered from any stomach or intestinal disorders.
  • Allergy with Mifepristone or related products.
  • Avoid the use of tobacco and inhibits smoking also.
  • Don't use if other birth control method already adopted like IUDs.
  • Don't use as prevention method for STDs.